Generally speaking, the larger the clubhead, the more forgiving a driver tends to be. This is why the USA has set the maximum driver clubhead size to 460 cc.
In most cases, having a larger clubhead allows manufacturers to increase the MOI (moment of inertia), which is one of the primary determinants of how forgiving a driver is.
With the TSi3, Titleist has elected to use every cubic centimeter available to them, maxing out at 460 cc’s. However, the head size of the TSi4 is only 425 cc, which is a reduction of about 8%.
In addition to clubhead size, the TSi4 also has the CG set as far forward as possible. This reduces the MOI (forgiveness) and lowers the backspin numbers that the club will produce.
All of these attributes result in a driver that can produce amazingly long bullet drives that power through the wind and get plenty of run after landing. However, in order to hit these bullet drives with the TSi4, you need to have a fast swing speed (110 mph or more), you need to have a positive angle of attack, and you need to hit the center of the clubface consistently.
While this isn’t too much of an issue for an experienced professional, it can be quite an ask for a normal amateur.
Based on how demanding the TSi4 is, it’s fair to say that most amateurs will be better served by the TSi3, which is less demanding, more foriving and more customizable.